- January: Pyramid of the Sun and Avenue of the Dead, Teotihuacan
- February: “The Conquest of Tenochtitlan” from the Conquest of Mexico series, Mexico
- March: Rubbing of the sarcophagus lid of King Pakal, whose tomb lies under the Temple of the Inscriptions at Palenque
- April: Pages 52 & 53 of the eclipse tables from the Dresden Codex, one of only four Mayan codices to survive
- May: El Caracol (“The Observatory”), Chichen Itza
- June: The Aztec Calendar Stone, now in the National Anthropology Museum in Mexico City
- July: Stele 6, found at Tortuguero: the only Mayan inscription specifically mentioning 2012
- August: Portrait of Michel de Nostredame, better known as Nostradamus, the famous French seer
- September: The Carina Nebula photographed from the Hubble Space Telescope
- October: The surface of our sun with a massive solar flare
- November: The Pyramid of Kukulkan (El Castillo) in Chichen Itza with storm clouds approaching
- December: Tourist with the Temple of Kukulkan at Chichen Itza reflected in sunglasses
- 2012 Calendar Cover